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Cat No. | Product Name | Synonyms | Targets |
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T40811 | Eflornithine | RMI71782,α-difluoromethylornithine,DFMO,MDL71782 | |
Eflornithine is an irreversible inhibitor that specifically targets the enzyme ornithine decarboxylase. It serves as a therapeutic medication for two conditions: the treatment of African trypanosomiasis and the managemen... | |||
T2593 | Eflornithine hydrochloride hydrate | Difluoromethylornithine hydrochloride hydrate,α-difluoromethylornithine hydrochloride hydrate,Eflornithine hydrochloride,MDL-71782 hydrochloride hydrate,DFMO hydrochloride hydrate,RMI-71782 hydrochloride hydrate,Eflornithine hydrochloride Monohydrate | Decarboxylase |
Eflornithine hydrochloride hydrate (RMI-71782 hydrochloride hydrate) is a specific, irreversible inhibitor of ornithine decarboxylase. | |||
T22831 | Protein kinase inhibitor H-7 dihydrochloride | H-7 dihydrochloride | PKC |
Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor. Protein kinase inhibitor H-7 dihydrochloride (100 μM) significantly inhibits TPA (skin tumor promoter, 12-O-... | |||
T11812L | L-Eflornithine monohydrochloride | L-α-difluoromethylornithine monohydrochloride,L-RMI71782 monohydrochloride,L-DFMO monohydrochloride | Others |
L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 µM, and a Kinact of 0.15±0.03 min-1. L-Eflornithine monohydrochloride (L-DFMO monohydrochloride) is an enantiomer of Eflornit... | |||
T11812 | L-Eflornithine | L-α-difluoromethylornithine,L-RMI71782,L-DFMO | Others |
L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 μM, and a Kinact of 0.15±0.03 min-1. L-Eflornithine is an enantiomer of Eflornithine. | |||
T68771 | 2-Fluoromethylornithine | ||
2-Fluoromethylornithine is an ornithine decarboxylase antagonist. | |||
T40789 | Eflornithine hydrochloride | MDL71782hydrochloride,RMI71782hydrochloride,DFMO hydrochloride,α-difluoromethylornithinehydrochloride | |
Eflornithine hydrochloride, a specific and irreversible inhibitor of ornithine decarboxylase enzyme, is a medication used for the treatment of African trypanosomiasis and excessive facial hair growth in women. |
Cat No. | Product Name | Synonyms | Targets |
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TN1774 | Isobavachromene | Others , Antibacterial | |
Isobavachromene is an inhibitor of NADH-Ubiquinone oxidoreductase and ornithine decarboxylase. Isobavachromene has antifungal activity. | |||
T1611 | Isotretinoin | 13-cis-Retinoic acid | Retinoid Receptor , Endogenous Metabolite , Autophagy |
Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. Isotretinoin is a naturall... | |||
T5S1331 | Herbacetin | c-Met/HGFR , Akt | |
1. Herbacetin induces apoptosis in HepG2 cells, by ROS and PI3K/Akt pathway. 2. Herbacetin suppresses the HGF-induced motility of human breast cancer MDA-MB-231 cells by inhibiting c-Met and Akt phosphorylation. |
Cat No. | Product Name | Species | Expression System |
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TMPJ-00839 | ODC1 Protein, Human, Recombinant (His) | Human | E. coli |
Ornithine decarboxylase (ODC1) is an enzyme which belongs to the Orn/Lys/Arg decarboxylase class-II family. ODC1 is the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. ... |